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Gentle and Non-Acidic. Unique Vitamin C Formula. Vegetarian. 24-Hour Immune Support. Dietary Supplement. Non-GMO. Suitable for Vegans. Ester-C® is a unique breakthrough Vitamin C formula containing naturally occurring metabolites. Metabolites help enhance the retention of Vitamin C by your white blood cells, an important part of your immune system. Ester-C®'s water-based manufacturing process neutralizes pH, making it non-acidic and gentle on the stomach. In a daily 1,000 mg dose, Ester-C® delivers 24-hour immune support..so once a day is all you need.