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Natural Factors Astaxanthin Plus 4mg Softgels Natural Factors Astaxanthin Plus combines AstaREAL astaxanthin, one of nature’s most powerful antioxidants, with lutein and zeaxanthin to protect cells from oxidative damage.* Natural Factors Astaxanthin Plus is cardioprotective, supports the immune system, and protects the skin from premature aging and other health risks associated with UV exposure. Astaxanthin also helps maintain gastrointestinal and eye health.