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Natural Factors HerbalFactors Horse Chestnut & Grape Seed 350mg Horse Chestnut & Grape Seed formula combines two proven nutrients for vein health. Horse chestnut improves venous tone and blood flow, and inhibits enzymes that can weaken blood vessels, causing varicose veins and hemorrhoids.* Antioxidant grape seed extract protects capillaries, veins and arteries from free radical damage.