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MacuGuard® Ocular Support with Saffron provides lutein, zeaxanthin, vitamin A, C3G, and saffron: hard to get nutrients that help support the eye’s delicate photoreceptor cells, promote macular and retinal health and support healthy night vision. It is our best-selling formula for eye health.

The nutrients our eyes need are hard to come by. That’s why we created our best-selling MacuGuard® formula.
MacuGuard® Ocular Support with Saffron Benefits
Delivers comprehensive ocular nutritional support in a single softgel
Contains lutein, two forms of zeaxanthin & saffron compounds
Contains phospholipids to promote lutein absorption
Contains berry flavonoids to support night vision

Product Details

Your eyes can undergo changes as a factor of normal aging.1,2 But certain focused nutrients can have a beneficial effect on normal eye health.3 That’s why we created our MacuGuard® eye health support formulas.

Macular pigment density: vital for healthy vision

Maintaining healthy levels of carotenoids, like lutein and zeaxanthin that make up the macular pigment in your retina is essential for maintaining eye health.4 Macular pigment density is also essential to healthy vision.5,6 But levels of macular pigment gradually decline over time.7 That's why MacuGuard® contains lutein as well as trans-zeaxanthin and meso-zeaxanthin, powerful carotenoids that are difficult to get from diet alone.

Lutein and zeaxanthin support underlying photoreceptor cells against oxidative stress, inhibit the effects of excess light and promote a healthy inflammatory response to support eye health. 8-11 We’ve also added Alpha-carotene which your body needs to make vitamin A. Vitamin A is essential to maintain a healthy eye structure and function.12

Phospholipids for lutein absorption

Phospholipids help support phytonutrients like lutein reach the bloodstream. They also help protect active compounds from degradation.13 Pre-clinical evidence indicates that phospholipids can promote lutein absorption, encouraging the circulation and accumulation of lutein within the retina.14-16

Nutrition for night vision: C3G berry flavonoids

MacuGuard® also contains cyanidin-3-glucoside, a flavonoid derived from European black currant berry extract. Pre-clinical evidence suggests that this potent antioxidant encourages the regeneration of rhodopsin, a light-sensitive retinal pigment which promotes visual acuity in low-light conditions.17-19

Age-related decline of rhodopsin plays a role in the loss of night vision, so this nutrient may support healthy night vision in older eyes.20 C3G can also help inhibit inflammation to support eye health.21

Vision-enhancing benefits of saffron

This formula also includes saffron to support healthy vision.22-24 People supplementing with saffron showed seeing an average of two additional lines on the Snellen eye chart commonly used by doctors to test vision.23

Serving Size 1 softgel

Amount Per Serving

MacuGuard® proprietary blend

173 mg

Phospholipids, marigold extract (Tagetes erecta) (flower) [providing 10 mg free lutein, 4 mg meso-zeaxanthin & trans-zeaxanthin], mixed carotenoids [providing 1.24 mg α-carotene]


Saffron extract (stigma)

20 mg

C3G (cyanidin-3-glucoside) [from European black currant extract (fruit)]

2.2 mg

Other ingredients: extra virgin olive oil, gelatin, glycerin, safflower oil, beeswax, palm oil, purified water, acacia gum, annatto color, potato maltodextrin.


LuteinPlus® and Mz® are registered trademarks of Nutriproducts Ltd., UK, licensed under U.S. Patent 8,623,428.

Dosage and Use
  • Take one (1) softgel daily, with food, or as recommended by a healthcare practitioner.
  • Based on scientific studies, this formula is enhanced with phospholipids to increase lutein absorption.
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

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