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Natural Factors Niacin Inositol Hexanicotinate 500mg Capsules Natural Factors Niacin, also referred to as vitamin B3, helps maintain healthy cholesterol levels and assists enzymes in the breakdown and utilization of carbohydrates, fats, and proteins. Natural Factors Niacin delivers niacin in the form of inositol hexanicotinate, which minimizes the flushing effect and other side effects associated with other forms of niacin.