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Natural Factors Phosphatidyl Choline 420mg Natural Factors Phosphatidylcholine (also referred to as phosphatidylcholine) is the nutrient precursor to acetylcholine, an important brain chemical (neurotransmitter) involved in both memory and thought. In healthy people, phosphatidylcholine is said to enhance mental function and is needed to build cell membranes, improve nerve cell efficiency, and repair neurons.